blood tests, AI and more

The Boston Globe•November 26, 2025•health

Key Points:

Liquid biopsy tests like Galleri aim to revolutionize cancer care by detecting malignancies early, potentially enabling treatment before cancers become deadly, addressing the gap where 70% of cancers currently have no screening tests.
While promising, these tests face challenges such as false positives leading to unnecessary procedures, false negatives missing aggressive cancers, and detecting cancers at advanced stages due to higher DNA shedding.
Studies show Galleri can identify cancer location correctly 92% of the time and detect many cancers without existing screening methods, but nearly half of detected cases were already advanced, highlighting the need for improved early detection.
Researchers are exploring AI and other biomarkers to better identify high-risk individuals for targeted screening, such as using medical records patterns for pancreatic cancer risk and AI

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