GLP-1R-GIPR-PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice

GLP-1R-GIPR-PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice

Nature health

Key Points:

  • In recent years, there has been a remarkable resurgence in drugs to treat obesity and its related co-morbidities. A standout example is tirzepatide, a co-agonist at the receptors for GLP-1 and GIP. In

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